Isoimperatorin Induces Apoptosis of Nasopharyngeal Carcinoma Cells via the MAPK/ERK1/2 Signaling Pathway
Effect of isoimperatorin on CNE2 cell apoptosis is attenuated by ISO. Western blot analysis shows the expression of p-c-RAF, p-MEK, and p-ERK1/2 (a), PCNA, XIAP, and survivin (b), and Bax and Bcl-2 (c) in CNE2 cells. vs control group: ; vs ISOIMP group, ;; dual-fluorescence flow cytometry cellometer image cytometer (K2) was used to detect the change of apoptotic rate of CNE2 cells after ISO and isoimperatorin intervention (d) vs control group: ; vs ISOIMP group, ;.
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