Acute and Subchronic Toxicity Profile of a Polyherbal Drug Used in Sri Lankan Traditional Medicine

Table 4

Changes in the body weight of Wistar rats (subacute or subchronic toxicity study).

Treatments	Body weight (g)
	1^st week	2^nd week	3^rd week	4^th week
Healthy control rats	268.15 ± 3.72	277.12 ± 2.53	285.50 ± 3.42	292.18 ± 4.01
Hot water extract treated rats (1.0 g/kg)	266.60 ± 2.03	268.32 ± 3.05	274.64 ± 2.83	280.52 ± 2.12
Water : acetone extract treated rats (0.5 g/kg)	264.64 ± 1.20	268.42 ± 2.94	270.36 ± 2.58	278.20 ± 3.01
Water : acetone extract treated rats (0.5 g/kg)	268.70 ± 2.54	274.16 ± 3.47	276.78 ± 3.79	280.38 ± 2.69
Water : acetone extract treated rats (1.5 g/kg)	266.50 ± 2.48	268.14 ± 4.06	269.24 ± 1.94	270.62 ± 1.73

Each data point is expressed as mean ± SEM (n = 6/group). Results are significant compared to the control group at  < 0.05.