Research Article

Acute and Subchronic Toxicity Profile of a Polyherbal Drug Used in Sri Lankan Traditional Medicine

Table 5

Effect of the polyherbal drug on consumption of food in healthy rats at weekly intervals.

TreatmentAverage consumption of food (g/day)
1st weak2nd weak3rd weak4th weak

Healthy control rats22.00 ± 0.5922.33 ± 0.8120.50 ± 1.0420.16 ± 0.93
Hot water extract (1.0 g/kg)22.50 ± 1.2422.00 ± 1.5220.83 ± 0.6220.33 ± 0.81
Water : acetone extract (0.5 g/kg)21.66 ± 0.4822.66 ± 1.0220.00 ± 1.7120.66 ± 1.09
Water : acetone extract (0.5 g/kg)21.33 ± 0.7120.50 ± 0.3419.66 ± 0.6119.91 ± 0.92
Water : acetone extract (1.5 g/kg)20.83 ± 0.9020.33 ± 1.6919.75 ± 1.2419.58 ± 0.53

Each data point is expressed as mean ± SEM (n = 6/group). Results are significant compared to the control group at  < 0.05.