Acute and Subchronic Toxicity Profile of a Polyherbal Drug Used in Sri Lankan Traditional Medicine

Table 6

Effect of the polyherbal drug on intake of water in healthy rats at weekly intervals.

Treatment	Average consumption of water (mL/day)
	1^st weak	2^nd weak	3^rd weak	4^th weak
Healthy control rats	66.66 ± 0.86	62.50 ± 0.92	61.66 ± 1.09	63.33 ± 0.72
Hot water extract (1.0 g/kg)	64.16 ± 0.75	64.16 ± 0.87	63.47 ± 1.12	62.84 ± 1.36
Water : acetone extract (0.5 g/kg)	63.58 ± 1.24	64.90 ± 1.53	62.28 ± 1.03	61.15 ± 1.26
Water : acetone extract (0.5 g/kg)	64.10 ± 1.49	62.73 ± 1.81	63.61 ± 1.42	62.44 ± 1.69
Water : acetone extract (1.5 g/kg)	64.25 ± 0.83	61.47 ± 0.46	62.26 ± 0.80	61.59 ± 0.85

Each data point is expressed as mean ± SEM (n = 6/group). Results are significant compared to the control group at  < 0.05.