Efficacy and Safety of Modified Duhuo Jisheng Decoction in the Treatment of Lumbar Disc Herniation: A Systematic Review and Meta-Analysis

Table 1

Characteristics of all the trials included in the meta-analysis.

Authors	Country	Study type	Sample size D : C	Mean age (years) D : C	Gender M : F	Intervention	Treatment duration (days)
Li and He [3]	China	RCTs	124 (64/60)	38.5/37.6	114/10	3 times, 100 mL, every day^†; DSSRC, 1 time, 100 mg, every day^‡	20^†; 20^‡
Li [6]	China	RCTs	100 (50/50)	52.2/53.1	46/54	2 times, every day^†; DL-LAP, 4 times, 900 mg, every day^‡	NP^†; NP^‡
Li [10]	China	RCTs	84 (42/42)	49.5/49.5	49/35	3 times, 100 mL, every day^†; DSSRC, 1 time, 100 mg, every day^‡	NP^†; NP^‡
Ma [4]	China	RCTs	80 (40/40)	48.5/48	45/35	3 times, 250 mL, every day^†; aceclofenac, 2 times, 100 mg, every day^‡	30^†; 20^‡
Ma et al. [5]	China	RCTs	68 (34/34)	48.3/48.3	41/27	2 times, every day^†; DSECT, 3 times, 25 mg, every day^‡	21^†; 21^‡
Mao [7]	China	RCTs	124 (64/60)	39.5/38.6	98/26	3 times, 100 mL, every day^†; meloxicam, 1 time, every day^‡	20^†; 20^‡
Rui and Zhao [12]	China	RCTs	100 (50/50)	38.8/39.4	80/20	NP^†; DSECT, 1 time, 100 mg, every day^‡	NP^†; 28^‡
Wang and Yang [9]	China	RCTs	100 (50/50)	NP	65/35	2 times, every day^†; 3 times, DSECT, 25 mg; ibuprofen, 200 mg; indomethacin, 25 mg, every day^‡	15^†; 15^‡
Wei and Yang [11]	China	RCTs	64 (32/32)	41.5/43.2	38/26	2 times, every day^†; NP^‡	28^†; NP^‡
Xie and Du [8]	China	RCTs	132 (66/66)	NP	NP	3 times, every day^†; 2 times, ICST, 213 mg; mannitol, 250 ml; vitamin B1, 10 mg, every day^‡	21^†; 21^‡
Xue [16]	China	RCTs	60 (30/30)	40.5/40.2	37/23	2 times, every day^†; DSECT, 3 times, 25 mg, every day^‡	21^†; 21^‡
Zhang et al. [14]	China	RCTs	350 (175/175)	42.8/41.7	189/161	2 times, every day^†; DSECT, 1 time, 100 mg, every day^‡	14^†; 14^‡
Zhang and Zhong [15]	China	RCTs	100 (50/50)	NP	49/51	3 times, 250 mL, every day^†; DSECT, 2 times, 100 mg, every day^‡	20^†; 20^‡
Zou [13]	China	RCTs	74 (37/37)	55.2/55.4	41/33	1 time, every day^†; NP^‡	30^†; 30^‡

DHJSD: Duhuo Jisheng Decoction; RCTs: randomized controlled trials; DSSRC: diclofenac sodium sustained-release capsule; DSECT: diclofenac sodium enteric-coated tablets; DL-LAP: DL-Lysine Aspirin Powder; ICST: ibuprofen codeine sustained tablets; NP: not provided. ^†D: DHJSD group, ^‡C: control group.