Research Article

The Therapeutic Effect of Shark Liver Oil in a Rat Model of Acetic Acid-Induced Ulcerative Colitis

Table 1

Histological grading of ulcerative colitis.

Scoring parametersScore definition

Inflammation severity0: none
1: mild
2: moderate
3: severe

Inflammation extent0: none
1: mucosa
2: mucosa and submucosa
3: transmural

Crypt damage0: none
1: basal 1/3 damaged
2: basal 2/3 damaged
3: crypts lost, surface epithelium intact
4: crypts lost, surface epithelium lost

Percentage of involvement0: 0%
1: 1–25%
2: 26–50%
3: 51–75%
4: 76–100%

Regeneration0: complete regeneration or normal tissue
1: almost complete regeneration
2: regeneration with crypt depletion
3: surface epithelium not intact
4: no tissue repair