Traditional Herbal Medicine Candidates as Complementary Treatments for COVID-19: A Review of Their Mechanisms, Pros and Cons

Figure 4

Quinine sulphate has activity as an antiviral agent by enhancing the synthesis of RIG-I and IFN-alpha synthesis. Then, both will block the translation of viral mRNA through the activation of PKR and degrade the viral poly mRNA by activating RNAse (L) Therefore, no viral protein is synthesised.