Research Article

Applying Complex Network and Cell-Cell Communication Network Diagram Methods to Explore the Key Cytokines and Immune Cells in Local Acupoint Involved in Acupuncture Treating Inflammatory Pain

Table 3

Key cells in ST36 acupoint based on CCC network diagram analysis.

Target cellSecretory cellCellsd

CFA conditionDay 1TH1 cellsTH2 cellsTH1 cells
Day 7TH1 cellsTH2 cellsTH1 cells
Day 15Endothelial cellsEndothelial cellsEndothelial cells

CFA + MA conditionDay 1CD4+T cellsMonocyte macrophagesFibroblast cells
Day 7CD4+T cellsMonocyte macrophagesFibroblast cells
Day 15NeutrophilsMonocyte macrophagesFibroblast cells