Antistaphylococcal Activity of Extracts, Fractions, and Compounds of Acacia polyacantha Wild (Fabaceae)

Table 1

Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) in μg/mL of crude extracts from Acacia polyacantha and ciprofloxacin against S. aureus strain.

Tested samples, MICs in μg/mL, and MBCs in parentheses
Bacteria	Stem bark extract	Leaf extract	Root extract	Ciprofloxacin
ATCC25923	256(-)	512(-)	1024(-)	8(-)
MRSA 3	256(-)	128(-)	128(-)	2(-)
MRSA 4	256(-)	128(-)	1024(-)	1
MRSA 6	1024(-)	256(-)	1024(-)	2
MRSA 8	512(-)	1024(-)	1024(-)	2(-)
MRSA 9	512(-)	512(-)	1024(-)	2(-)
MRSA 11	1024(-)	512(-)	1024(-)	2(16)
MRSA 12	1024(-)	512(-)	1024(-)	2(-)
MSSA 01	—	512(-)	1024(-)	2(-)
SA 01	16(-)	128(-)	512(-)	≤0.5(-)
SA 07		—	64(-)	≤0.5(-)
SA 18	32(-)	16(-)	512(-)	≤0.5(8)
SA 23	—	512(-)	64(-)	≤0.5(8)
SA 88	—	128(-)	—	≤0.5(-)

(-): ≥1024 μg/mL; MIC: minimum inhibitory concentration; MBC: minimum bactericidal concentration; MRSA: methicillin-resistant Staphylococcus aureus; SA: Staphylococcus aureus; MSSA: methicillin susceptible Staphylococcus aureus.