Research Article

Toxicity and Its Mechanism Study of Arecae semen Aqueous Extract in Wistar Rats by UPLC-HDMS-Based Serum Metabolomics

Figure 4

PCA plots with the scores of the first two principal components (a) exhibiting the scatter between 1500 mg/kg/d dose of ASAE-induced group (blue square) and the control group (green circle) in the ESI negative ion mode, R2X = 0.640, Q2(cum) = 0.484, (b) exhibiting the scatter between 4500 mg/kg/d dose of ASAE-induced group (red triangle) and the control group (green circle) in the ESI negative ion mode, R2X = 0.659, Q2(cum) = 0.170, (c) exhibiting the scatter between 1500 mg/kg/d dose of ASAE-induced group (blue square) and the control group (green circle) in the ESI positive ion mode, R2X = 0.487, Q2(cum) = 0.135, and (d) exhibiting the scatter between 4500 mg/kg/d dose of ASAE-induced group (red triangle) and the control group (green circle) in the ESI positive ion mode, R2X = 0.548, Q2(cum) = 0.0519.
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