Toxicity and Its Mechanism Study of <i>Arecae semen</i> Aqueous Extract in Wistar Rats by UPLC-HDMS-Based Serum Metabolomics

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left" rowspan="2">Compounds</td><td class="align_center" colspan="2">Contents (mg/mL)</td></tr><tr class="thead"><td class="align_center">1500 (mg/kg/d)</td><td class="align_center">4500 (mg/kg/d)</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Arecoline</td><td class="align_center">0.67</td><td class="align_center">2.35</td></tr><tr><td class="align_left">Guvacoline</td><td class="align_center">0.32</td><td class="align_center">0.69</td></tr><tr><td class="align_left">Arecaidine</td><td class="align_center">0.41</td><td class="align_center">1.12</td></tr><tr><td class="align_left">Guvacine</td><td class="align_center">1.22</td><td class="align_center">4.23</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>The concentrations of arecoline, guvacoline, arecaidine, and guvacine in the ASAE samples (<i>n</i> = 3).</div>

Evidence-Based Complementary and Alternative Medicine

tab1

Table 1

Table 1: Toxicity and Its Mechanism Study of <i>Arecae semen</i> Aqueous Extract in Wistar Rats by UPLC-HDMS-Based Serum Metabolomics 

Evidence-Based Complementary and Alternative Medicine

Toxicity and Its Mechanism Study of Arecae semen Aqueous Extract in Wistar Rats by UPLC-HDMS-Based Serum Metabolomics

Table 1