Research Article

Evaluation of Antiulcer Activity of 80% Methanol Extract and Solvent Fractions of the Root of Croton macrostachyus Hocsht: Ex Del. (Euphorbiaceae) in Rodents

Table 2

Antiulcer activity of crude extract of the root of C. macrostachyus on acidified ethanol-induced ulcer model in mice.

GroupsAverage ulcer number (UN)Ulcer index% of ulcer inhibition

NC5.3322.50 ± 1.95
CM1003.3317.00 ± 1.07e224.44
CM2002.1712.17 ± 0.38a145.93
CM4000.838.50 ± 2.80a362.22
SUC1000.677.04 ± 2.87a3b280

Values are expressed as Mean ± SEM, n = 6, , , ,acompared to NC, bcompared to CM100, ccompared to CM200, dcompared to CM400, and ecompared to SUC100. Statistically analyzed by one-way ANOVA followed by the Tukey test.