Acute and Subchronic Oral Safety Profiles of the Sudarshana Suspension

Table 4

Effects of oral administration of SP and SS on the haematological parameters of rats’ blood after 42-day period of oral administration.

Blood parameters	Groups
	Control	S. powder	S. suspension
White blood cells (WBC) (10^3/μl)	8.18 ± 0.17	7.9 ± 0.13	8.02 ± 0.15
Neutrophil (%)	33.18 ± 3.2	28.65 ± 2.80	32.21 ± 2.82
Lymphocytes (%)	55.44 ± 1.84	59.54 ± 2.60	56.88 ± 2.58
Monocyte (%)	4.35 ± 1.23	5.92 ± 1.40	5.35 ± 1.0
Eosinophil (%)	2.54 ± 0.55	1.78 ± 0.18	2.07 ± 0.40
Basophil (%)	2.6 ± 0.70	3.8 ± 0.67	3.5 ± 0.53
Red blood cells (RBC) (10^6/μL)	8.29 ± 0.35	7.8 ± 0.19	7.9 ± 0.19
Haemoglobin (Hb)	14.18 ± 0.39	14.3 ± 0.20	14.18 ± 0.27
Packed cell volume (PCV) (%)	48.94 ± 1.85	48.65 ± 1.26	48.41 ± 1.93
Mean corpuscular volume (MCV) (fL)	53.61 ± 2.15	53.97 ± 1.78	56.37 ± 1.51
Mean corpuscular haemoglobin (MCH) (pg)	24.05 ± 1.27	23.37 ± 0.86	24.05 ± 0.97
Mean corpuscular haemoglobin conc. (MCHC) (pg)	27.34 ± 1.08	26.8 ± 0.91	25.87 ± 1.28
RDW (%)	14.81 ± 0.11	15.0 ± 0.19	14.52 ± 0.08
Platelets (10^3/μL)	636.42 ± 2.73	631.71 ± 2.02	635.42 ± 2.28
MPV (fL)	3.25 ± 0.42	2.61 ± 0.16	2.7 ± 0.11

Values are expressed as mean ± SEM; n = 6.