Acute and Subchronic Oral Safety Profiles of the Sudarshana Suspension

Table 7

Effect on renal and hepatic functions following 7 days of oral administration of SS.

Biochemical parameters	Testing days and values
	Day 0	Day 3	value	Day 8	value
Haemoglobin (Hb) (g/dl)	12.71 ± 0.24	12.70 ± 0.24	0.28	12.74 ± 0.23	0.19
AST/GOT (IU/L)	28.86 ± 0.68	28.57 ± 0.73	0.12	28.89 ± 0.69	0.46
ALT/TGP (U/L)	23.12 ± 1.44	22.76 ± 1.42	0.16	23.20 ± 1.43	0.4
Gamma GT (IU/L)	11.68 ± 0.85	11.54 ± 0.79	0.35	11.29 ± 0.81	0.7
Alkaline phosphatase (IU/L)	210.05 ± 8.44	209.13 ± 8.20	0.12	209.10 ± 8.15	0.11
Urea (mmol/L)	2.83 ± 0.13	2.80 ± 0.13	0.19	2.84 ± 0.12	0.4
Creatinine (mg/dl)	0.78 ± 0.01	0.78 ± 0.01	0.49	0.79 ± 0.01	0.25

All the values are expressed as mean ± SEM; n = 35. , not significant.