Effects and Mechanisms of Dendrobium officinalis Six Nostrum for Treatment of Hyperuricemia with Hyperlipidemia

Figure 4

Effect of DOS on inflammatory proteins in kidney and intestinal tissues. (a) Kidney NLRP3 IHC pictures (×400). (b) Kidney Caspase IHC pictures (×400). (c) Intestinal TLR4 IHC pictures (×400). (d) Intestinal NLRP3 IHC pictures (×400). (e) Kidney NLRP3 OD value. (f) Kidney Caspase-1 OD value. (g) Intestinal TLR4 OD value. (h) Intestinal NLRP3 OD value. NC—normal control; MC—model control; DOS-L—low dose of DOS (3.45 g/kg body weight); DOS-M—medium dose of DOS (6.90 g/kg body weight); DOS-H – high dose of DOS (13.80 g/kg body weight). The data were expressed as mean ± SD of 8–10 rats in each group. ; , compared with normal control group; ; , compared with model control group.

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