Research Article

Network Pharmacology-Based Approach to Revealing Biological Mechanisms of Qingkailing Injection against IschemicStroke: Focusing on Blood-Brain Barrier

Figure 5

QKL possessed neuroprotective effect and attenuated BBB disruption. (a) Nissl-stained brain tissues after MCAO/reperfusion treatment (magnification ×400). (b) Bar graph indicates necrotic cell death score in penumbra area for each group. (c) Representative figure of BBB leakage evaluated by Evan Blue (EB). (d) Quantitative analysis of EB leakage. (e) FITC-dextran leakage in live mice. Data are reported as means ± SEM. vs. Sham group, vs. Ischemia group (n = 6 per group).
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