Ningdong Granule Upregulates the Striatal DA Transporter and Attenuates Stereotyped Behavior of Tourette Syndrome in Rats

Figure 3

DAT expression in different groups at week 8. Immunochemistry labeling for DAT in different groups was performed at week 8 during medication (n = 5/group). Insets in (A1-A4) are shown at high magnification in (B1-B4); the arrows point to the area with DAT positive expression (A1-B4). Scale bars = 50 μm in (A4) (applies to A1-A4); scale bars = 25 μm in (B4) (applies to B1-B4). Graphical representation shows more positive area of DAT in the NGD-treated group than the Hal and TS group (C) (n = 5). Representative western blots of DAT expression (n = 5/group), and GAPDH was a loading control (D). Semiquantitative measurements were obtained by normalizing GAPDH loading (E). . CTR stands for the CTR group microinfused by normal sera; TS stands for the TS model control without medication; Hal stands for the Haloperidol treatment group; NDG stands for the NDG treatment group.

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