Research Article

Efficacy of Active Charcoal and Mannitol in Patients with Haff Disease Caused by the Consumption of Crayfish (Procambarus clarkii): A Retrospective Cohort Study

Table 1

Demographic and clinical characteristics of Haff disease patients.

VariableACM group (n = 22)Non-ACM group (n = 46) value

Age (years)34.4 ± 9.933.6 ± 8.10.731

Gender (male/female)0.392

BMI (kg/m2)21.2 ± 1.521.5 ± 1.50.389

Time from crayfish eaten to symptom onset (hours)3.4 ± 1.73.9 ± 2.00.296

Duration of hospital stays (days)7.5 (6.0–8.0)8.0 (6.8–10.0)0.032

Symptoms
 Myalgia2246
 Shortness of breath670.237
 Nausea or vomiting540.11
 Abdominal pain430.139
 Weakness2246
 Brown urine/hematuria340.531

Medical histories
 Hypertension340.531
 Coronary heart disease110.588
 Diabetes mellitus210.194

Admission laboratory values
 Creatinine (μmol/L)68.6 ± 16.176.3 ± 20.00.119
 BUN (mmol/L)7.3 ± 2.17.2 ± 3.10.81
 WBC (109/L)8.1 ± 2.89.3 ± 2.60.091
 Hematocrit (%)43.3 ± 4.943.5 ± 6.20.878

Remifentanil dose during the first 24 hours of hospitalization (mg)0.2 ± 0.60.4 ± 0.80.071

BUN, blood urea nitrogen; WBC, white blood cell; CK, creatine kinase; CK-MB, creatine kinase-muscle/brain; AST, aspartate transaminase; ALT, alanine transaminase; LDH, lactic dehydrogenase.