Anticancer Activity of Modified Tongyou Decoction on Eca109 Esophageal Cancer Cell Invasion and Metastasis through Regulation of the Epithelial-Mesenchymal Transition Mediated by the HIF-1α-Snail Axis

Figure 7

Relative OD values of HIF-1α and Snail fluorescent signals inhibited by MTD in both normoxia and hypoxia Note: in Group OM, HIF-1α and Snail fluorescent signals weakened remarkably, showing statistical difference from those in Group OC,  < 0.05. What is noteworthy, in Group HC, both signals strengthened greatly, showing statistical difference from those in Group OC,  < 0.05. In Group HM, both signals weakened significantly, showing statistical difference from those in Group HC,  < 0.05. Homogeneity of variance by one-way ANOVA; LSD test applied to compare statistical difference