Effect of Thunbergia laurifolia Herbal Tea on Glucose Homeostasis in Healthy Volunteers: A Single-Arm Phase I Study
Table 2
Biochemical and hematological parameters at baseline and at 2 weeks.
All (n = 20)
TL 9 gm/day (n = 10)
TL 12 gm/day (n = 10)
Baseline
2 weeks
value
Baseline
2 weeks
value
Baseline
2 weeks
value
Cortisol (ug/dL)
8.0 ± 2.6
8.2 ± 3.1
0.84
7.6 ± 2.8
7.0 ± 2.3
0.42
8.5 ± 2.4
9.3 ± 3.5
0.43
eGFR (ml/min/m2)
114 ± 23
107 ± 15
0.23
107 ± 14
106 ± 15
0.57
120 ± 29
108 ± 16
0.27
AST (U/L)
18 (16–24)
20 (16–24)
0.87
19 (16–25)
20 (18–23)
0.59
18 (14–25)
28 (16–28)
0.86
ALT (U/L)
15 (10–31)
16 (11–24)
0.62
14 (9–37)
16 (13–25)
0.44
16 (11–23)
15 (11–23)
0.86
TB (mg/dL)
0.5 (0.4–0.7)
0.5 (0.3–0.8)
0.47
0.6 (0.3–0.7)
0.6 (0.3–0.8)
0.58
0.5 (0.4–0.7)
0.5 (0.3–0.5)
0.06
Hematocrit (%)
39.3 ± 5.4
39.7 ± 4.5
0.46
39.2 ± 6.1
39.2 ± 4.4
1.00
39.4 ± 4.9
40.2 ± 4.8
0.07
WBC (cells/mm3)
5746 ± 1314
6212 ± 921
0.07
5365 ± 971
6130 ± 958
0.04
6126 ± 1542
6293 ± 926
0.66
Platelets (×103/μL)
274 ± 64
284 ± 69
0.35
269 ± 67
277 ± 79
0.49
280 ± 65
290 ± 62
0.54
Data are presented as mean ± standard deviation or median and interquartile range. A value <0.05 indicates statistical significance. Abbreviations: eGFR, estimated glomerular filtration rate; AST, aspartate transaminase; ALT, alanine transaminase; TB, total bilirubin; WBC, white blood cell count.
