Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Exerts Anti-Breast Cancer Effect via miR-200c-PDE7B/PD-L1-AKT/MAPK Axis

Table 1

Screening extracts from HDSB and EA11 on cell proliferation (n = 3).

Groups	Extracts/fractions	Dose (μg/ml)	Inhibition (%)	IC50 (μg/ml)	Yield (%)
Control	—	—	0.00
HD	Water extract	250	43.75	336.36	13.48
		500	53.15
		1000	81.68
SB	Water extract	250	45.67	270.97	18.22
		500	59.51
		1000	58.87
HS12	Water extract	250	47.31	292.18	15.69
		500	56.53
		1000	74.56
HS21	Water extract	250	32.89	603.97	18.12
		500	43.83
		1000	59.22
HS11	Water extract	250	50.78	226.93	18.38
		500	68.52
		1000	80.69
EA11	Ethyl acetate fraction	62.5	80.41	30.28	0.26
		125	91.71
		250	94.58
		500	97.06
		1000	97.14
Tax		1 (μM)	70.50

Cell viability of 4T1 cells treated with extracts from HDSB and EA11 was determined by MTT assay. C: vehicle control; EA11: ethyl acetate fraction from HS11.