Research Article

Exercise Preconditioning Plays a Protective Role in Exhaustive Rats by Activating the PI3K-Akt Signaling Pathway

Table 1

The effect of EP on the cardiac function parameters of exhausted rats.

ConEEEPEP + EELY + EP + EELY

Parameter
 CO (ml/min)50.78 ± 4.3542.04 ± 3.7054.95 ± 4.0546.28 ± 3.8942.15 ± 3.6251.03 ± 3.20
 SV (μL)136.25 ± 17.22105.44 ± 10.77150.38 ± 12.03121.38 ± 14.03107.25 ± 10.77131.75 ± 16.51
 HR (bpm)374.50 ± 31.78401.75 ± 22.75349.63 ± 17.52388.38 ± 22.04395.50 ± 23.84367.63 ± 29.48
 Ves (μL)101.25 ± 9.82140.13 ± 13.2786.25 ± 12.31126.54 ± 10.79142.04 ± 17.8297.88 ± 13.00
 Ved (μL)212.50 ± 11.14236.50 ± 20.95196.25 ± 12.88220.00 ± 16.74229.88 ± 12.22215.50 ± 15.46
 Pes (mmHg)121.50 ± 15.3497.38 ± 10.65123.50 ± 17.25111.00 ± 12.28103.00 ± 7.96118.38 ± 13.76
 Ped (mmHg)3.83 ± 0.584.56 ± 0.333.42 ± 0.534.22 ± 0.374.49 ± 0.433.66 ± 0.45
Systolic indices
 EF (%)62.98 ± 7.4443.50 ± 5.8071.86 ± 11.9253.25 ± 9.4544.38 ± 3.7660.86 ± 10.91
 dp/dt max (mmHg/s)8922.38 ± 983.837211.50 ± 658.119733.75 ± 780.498091.50 ± 691.046929.38 ± 861.768672.38 ± 774.45
 ESPVR2.50 ± 0.361.45 ± 0.122.85 ± 0.501.90 ± 0.191.58 ± 0.202.53 ± 0.30
Diastolic indices
 EDPVR0.022 ± 0.0040.037 ± 0.0050.016 ± 0.0050.031 ± 0.0060.035 ± 0.0040.021 ± 0.003
 Tau9.57 ± 1.0313.63 ± 1.9510.03 ± 0.9411.74 ± 1.8313.28 ± 1.769.50 ± 0.85
 −dp/dt min (mmHg/s)6595.88 ± 544.955354.63 ± 527.547148.50 ± 608.646117.13 ± 509.855517.13 ± 523.946384.63 ± 555.96
Mechanoenergetics indices
 PE (mmHg ∗ μL)9916 ± 166513141 ± 22937679 ± 121010997 ± 188712034 ± 24479779 ± 1691
 SW (mmHg ∗ μL)16536 ± 228610875 ± 250620753 ± 26531396 ± 227311591 ± 201016285 ± 1824
 CE (%)61.88 ± 7.5745.63 ± 5.9572.38 ± 13.1856.25 ± 7.1348.00 ± 5.0763.12 ± 7.35