Effects of Acupuncture Treatment in Reducing Sleep Disorder and Gut Microbiota Alterations in PCPA-Induced Insomnia Mice

Figure 1

Grouping information of mice and corresponding intervention methods. Four groups of mice model were named blank, sham, Zop, and Acu, respectively. At 2 days after PCPA injection, zopiclone and acupuncture treatments were administered for 7 days. Normal saline was sham controlled for drugs such as PCPA and zopiclone. Penetrating on nonacupoints was sham controlled for acupuncture on acupoints (DU20, SP6, and HT7).