Effect of Aqueous Extract of Adansonia digitata Stem Bark on the Development of Hypertension in L-NAME-Induced Hypertensive Rat Model

Table 1

Body, heart, and kidneys weights after 3 weeks of treatment.

Parameters	Normotensive control	Hypertensive ctrl	LN + captopril	LN + AD100	LN + AD200
Body weight week 3 (g)	229.95 ± 2.02	209.37 ± 0.80^c	219.10 ± 1.68^δ	206.50 ± 1.38	216.35 ± 0.77^δ
Body W gain (% baseline)	26.11 ± 2.91	11.77 ± 3.48^a	12.79 ± 1.79	22.85 ± 1.55^α	14.95 ± 6.97^δ
Kidney W (g/100 g BW)	0.59 ± 0.05	0.79 ± 0.05^c	0.60 ± 0.01^δ	0.56 ± 0.01^δ	0.61 ± 0.01^δ
Heart W (g/100 g BW)	0.32 ± 0.02	0.37 ± 0.02^c	0.31 ± 0.03^δ	0.29 ± 0.01^β	0.34 ± 0.01
Left ventricle W (g/100 g)	0.13 ± 0.01	0.18 ± 0.01^a	0.16 ± 0.01	0.14 ± 0.01^δ	0.16 ± 0.01

Data are mean ± SEM (N = 6 per group). ANOVA + the Tukey test: ^c and ^a vs. the normotensive control group; ^δ, ^β, and ^α vs. the hypertensive control group. AD100/AD200 = extract doses 100 or 200 mg/kg. LN = N-NAME.