Effect of Aqueous Extract of Adansonia digitata Stem Bark on the Development of Hypertension in L-NAME-Induced Hypertensive Rat Model

Table 2

Effects of A. digitata extract on blood pressure and heart rate of hypertensive rats.

	SBP (mm Hg)	DBP (mm Hg)	MABP (mm Hg)	HR (BPM)
Normotensive control	113.24 ± 2.85	81.63 ± 3.26	92.17 ± 3.11	345.61 ± 4.65
Hypertensive control	189.49 ± 3.85^a	147.26 ± 5.40^a	161.34 ± 4.79^a	390.28 ± 16.45^c
LN + captopril	147.18 ± 5.82^α	118.65 ± 5.35^α	128.16 ± 5.32^α	349.98 ± 8.27
LN + AD100	172.64 ± 1.61^α	135.77 ± 1.50^β	148.06 ± 1.40^α	349.48 ± 13.16
LN + AD200	149.07 ± 7.86^α	115.10 ± 6.73^α	126.42 ± 7.08^α	341.04 ± 19.20^α

Data are mean ± SEM (N = 6 per group). ANOVA + the Tukey test: ^c and ^a vs. the normotensive control group; ^δ, ^β, and ^α vs. the hypertensive control group. AD100/AD200 = extract doses 100 or 200 mg/kg. DBP = diastolic arterial blood pressure. HR = heart rate. LN = N-NAME. MABP = mean arterial blood pressure. SBP = systolic arterial blood pressure.