Effect of Aqueous Extract of Adansonia digitata Stem Bark on the Development of Hypertension in L-NAME-Induced Hypertensive Rat Model
Table 4
Effects of A. digitata extract on blood lipid profile of hypertensive rats.
Normotensive control
Hypertensive ctrl
LN + captopril
LN + AD100
LN + AD200
Total cholesterol (mg/dL)
65.24 ± 1.28
80.47 ± 1.61b
66.02 ± 1.70α
69.90 ± 2.14
59.42 ± 1.85δ
Triglycerides (mg/dL)
33.29 ± 1.57
51.07 ± 0.86c
28.98 ± 1.58δ
40.82 ± 6.69
37.94 ± 3.26β
HDL-cholesterol (mg/dL)
30.28 ± 3.62
11.15 ± 0.64b
24.18 ± 3.27δ
18.87 ± 0.50
17.02 ± 2.69
LDL-cholesterol (mg/dL)
28.21 ± 4.47
45.52 ± 3.65b
36.04 ± 3.31
42.87 ± 1.58
34.81 ± 2.81
Cardiac risk ratio
2.15
7.22a
2.73β
3.70δ
3.49δ
Atherogenic index
0.04
0.66
0.08
0.34
0.35
Data are mean ± SEM (N = 6 per group). ANOVA + the Tukey test: c,b, and a vs. the normotensive control group; δ,β, and α vs. the hypertensive control group. AD100/AD200 = extract doses 100 or 200 mg/kg. LN = N-NAME.