Research Article

Effect of Aqueous Extract of Adansonia digitata Stem Bark on the Development of Hypertension in L-NAME-Induced Hypertensive Rat Model

Table 4

Effects of A. digitata extract on blood lipid profile of hypertensive rats.

Normotensive controlHypertensive ctrlLN + captoprilLN + AD100LN + AD200

Total cholesterol (mg/dL)65.24 ± 1.2880.47 ± 1.61b66.02 ± 1.70α69.90 ± 2.1459.42 ± 1.85δ
Triglycerides (mg/dL)33.29 ± 1.5751.07 ± 0.86c28.98 ± 1.58δ40.82 ± 6.6937.94 ± 3.26β
HDL-cholesterol (mg/dL)30.28 ± 3.6211.15 ± 0.64b24.18 ± 3.27δ18.87 ± 0.5017.02 ± 2.69
LDL-cholesterol (mg/dL)28.21 ± 4.4745.52 ± 3.65b36.04 ± 3.3142.87 ± 1.5834.81 ± 2.81
Cardiac risk ratio2.157.22a2.73β3.70δ3.49δ
Atherogenic index0.040.660.080.340.35

Data are mean ± SEM (N = 6 per group). ANOVA + the Tukey test: c, b, and a vs. the normotensive control group; δ, β, and α vs. the hypertensive control group. AD100/AD200 = extract doses 100 or 200 mg/kg. LN = N-NAME.