Effect of Aqueous Extract of Adansonia digitata Stem Bark on the Development of Hypertension in L-NAME-Induced Hypertensive Rat Model

Table 5

Effects of A. digitata on blood indicators of liver and kidney functions in hypertensive rats.

	Normotensive control	Hypertensive control	LN + captopril	LN + AD100	LN + AD200
ASAT (UI/L)	116.7 ± 6.13	179.7 ± 11.52^a	76.5 ± 7.31^α	94.8 ± 9.74^α	106.6 ± 7.22^α
ALAT (UI/L)	41.6 ± 1.36	55.3 ± 4.37^b	39.9 ± 2.09^β	38.4 ± 1.81^β	38.1 ± 1.64^β
Total protein (mg/dL)	1.3 ± 0.08	2.4 ± 0.11^a	1.8 ± 0.52^β	1.8 ± 0.05^β	1.8 ± 0.07^β
Creatinine (mg/dL)	4.8 ± 1.68	15.6 ± 1.29^a	4.9 ± 0.28^α	6.5 ± 0.28^α	3.5 ± 3.12^α
Sodium (mEq/L)	115.4 ± 1.89	139.4 ± 8.03^b	116.8 ± 1.63^α	100.6 ± 2.97^α	86.6 ± 7.38^α
Potassium (mEq/L)	10.9 ± 0.14	6.1 ± 0.06^b	8.8 ± 0.05^β	11.6 ± 0.36^α	15.2 ± 0.59^α
Chloride (mEq/L)	87.6 ± 1.23	93.0 ± 0.91^c	87.9 ± 0.30^δ	80.3 ± 0.21^α	86.0 ± 0.97^β

Data are mean ± SEM (N = 6 per group). ANOVA + the Tukey test: ^b and ^a vs. the normotensive control group; ^δ, ^β, and ^α vs. the hypertensive control group. AD100/AD200 = extract doses 100 or 200 mg/kg. LN = N-NAME.