In Vitro Screening for Acetylcholinesterase Inhibition and Antioxidant Activity of Quercus suber Cork and Corkback Extracts

Table 1

Lipophilic and polar extracts yields, composition in terms of total phenolic and total flavonoid contents, and antioxidant activity of ethanol-water extracts of cork and corkback samples from Quercus suber with particle sizes of 2-1 mm and 0.45–0.25 mm.

	Corkback		Cork
	2-1 mm	0.45–0.25 mm	2-1 mm	0.45–0.25 mm
Extraction yield of CH2Cl2 extract (%)	1.8 ± 0.1	3.6 ± 0.2	6.3 ± 1.0	6.6 ± 0.4
Extraction yield of EtOH-water extract (%)	8.3 ± 0.2	1.5 ± 0.1	1.8 ± 0.4	4.0 ± 0.1
Total phenolic (mg GAE/g extract)	435.1 ± 8.1	387.4 ± 11.1	202.9 ± 10.2	189.9 ± 19.6
Total flavonoid (mg CE/g extract)	127.4 ± 77.5	241.4 ± 84.3	90.0 ± 30.4	82.4 ± 8.7
Antioxidant capacity (mg TEAC/g extract)	57.4 ± 1.30	66.3 ± 0.1	19.6 ± 1.6	21.0 ± 0.2
IC50 values (μg extract/mL)	4.0 ± 0.1	5.2 ± 0.0	3.2 ± 0.1	3.2 ± 0.4
FRAP (mM TEAC/g extract)	9.2 ± 0.1	8.2 ± 0.2	3.1 ± 0.1	3.0 ± 0.1
FRAP (mg Fe^2+/g extract)	9222.4 ± 36.3	8120.5 ± 27.2	2995.3 ± 19.6	2991.9 ± 41.6

GAE: gallic acid equivalent; CE: catechin equivalent; TEAC: Trolox equivalent antioxidant capacity; FRAP: ferric ion reducing antioxidant potential.