Safety and Efficacy Evaluation of Traditional Chinese Medicine (Qingre-Lishi-Yishen Formula) Based on Treatment of Regular Glucocorticoid Combined with Cyclophosphamide Pulse in Children Suffered from Moderately Severe Henoch–Schonlein Purpura Nephritis with Nephrotic Proteinuria

Table 2

Basic clinical characteristics for all patients.

	Control group (n = 50)	QLYF group (n = 100)
Gender (male)	26 (52%)	56 (56%)	0.643
Age (year)	9.32 ± 2.68	9.52 ± 2.96	0.692
Additional symptom
GI involvement	23 (46%)	41 (41%)	0.559
Joint involvement	17 (34%)	21 (21%)	0.127
SBP (mmHg)	108.2 ± 12.6	109.5 ± 11.3	0.543
Albumin (g/L)	38.45 ± 5.21	33.11 ± 6.45	0.204
Urea (mmol/L)	4.45 ± 1.41	4.46 ± 1.52	0.970
Creatine (μmol/L)	46.57 ± 7.24	45.13 ± 7.93	0.283
eGFR(ml/min·1.73 m^2)	97.5 ± 16.0	99.6 ± 10.2	0.314
Triglyceride (mmol/L)	1.62 ± 0.90	1.44 ± 0.94	0.275
Cholesterol (mmol/L)	4.87 ± 1.11	4.63 ± 1.19	0.235
URBC (/HP)	26.88 ± 11.16	25.92 ± 11.06	0.618
24 h proteinuria (g)	2.76 ± 0.88	2.70 ± 0.73	0.659
Serum IgA (g/L)	1.97 ± 0.68	1.84 ± 0.66	0.278
Serum C3 (g/L)	0.993 ± 0.271	0.991 ± 0.251	0.976
Serum C4 (g/L)	0.732 ± 0.615	0.578 ± 0.459	0.170

GI: gastrointestinal; SBP: systolic blood pressure; URBC: urine red blood cell count; eGFR: estimated glomerular filtration rate; 24 h: 24 hour.