Luhong Formula Has a Cardioprotective Effect on Left Ventricular Remodeling in Pressure-Overloaded Rats

Table 1

Changes in body weight, heart weight, left ventricular weight, heart weight/body weight (HW/BW), and left ventricular weight/body weight (LVW/BW).

Group	n	Body weight (g)	Heart weight (mg)	Left ventricular weight (mg)	HW/BW (mg/g)	LVW/BW (mg/g)
Sham	8	520.13 ± 5.99	1251.19 ± 43.65	1047.59 ± 32.08	2.41 ± 0.20	2.01 ± 0.04
Model	7	493.00 ± 4.97	1489.22 ± 57.09	1212.19 ± 25.90	3.02 ± 0.09^Δ	2.46 ± 0.03^Δ
Perindopril	7	507.14 ± 3.85	1384.54 ± 21.26	1145.52 ± 24.61	2.73 ± 0.03	2.26 ± 0.03
LHF-H	8	503.25 ± 4.46	1399.20 ± 34.08	1161.63 ± 42.81	2.78 ± 0.04^##	2.31 ± 0.07
LHF-M	7	504.43 ± 4.86	1433.47 ± 34.72	1200.07 ± 42.78	2.84 ± 0.04^#★	2.38 ± 0.06^#
LHF-L	6	501.67 ± 3.67	1407.26 ± 23.89	1174.83 ± 23.87	2.81 ± 0.03^#▲	2.34 ± 0.03^#

Notes: sham: control group; model: model group; perindopril: perindopril group; LHF-L: low-dose LHF group; LHF-M: medium-dose LHF group; LHF-H: high-dose LHF group. Data are expressed as mean ± standard deviation (SD). compared with sham; compared with model; ^#, ^## compared with perindopril; compared with LHF-H; compared with LHF-M. The analysis between groups of body weight and left ventricular weight accorded with normality and homogeneity of variance, so we used one-way ANOVA test. Body weight (F: 26.185, ); left ventricular weight (F: 23.655, ). The analysis between groups of heart weight, HW/BW, and LVW/BW did not conform to the normality and homogeneity of variance, so we used rank sum test of two independent samples and obtained the Z value. Heart weight (); HW/BW (); LVW/BW ().