Luhong Formula Has a Cardioprotective Effect on Left Ventricular Remodeling in Pressure-Overloaded Rats

Table 6

Col1a1, Col3a1, eNOS, TGF-β1, VEGF, and VEGFR2 relative expression in myocardial tissue of experimental different groups.

Group	Col1a1	Col3a1	eNOS	TGF-β1	VEGF	VEGFR2
Sham	0.015 ± 0.002	0.010 ± 0.001	0.055 ± 0.003	0.020 ± 0.002	0.014 ± 0.001	0.004 ± 0.000
Model	0.080 ± 0.011^Δ	0.037 ± 0.002^Δ	0.019 ± 0.001^Δ	0.124 ± 0.017^Δ	0.063 ± 0.008^Δ	0.015 ± 0.001^Δ
Perindopril	0.029 ± 0.003	0.016 ± 0.001	0.039 ± 0.003	0.047 ± 0.009	0.040 ± 0.004	0.007 ± 0.001
LHF-L	0.063 ± 0.006^#★▲	0.031 ± 0.001^#★▲	0.026 ± 0.002^#★▲▲	0.092 ± 0.007^#★▲	0.051 ± 0.003^##★▲▲	0.012 ± 0.001^#★▲
LHF-M	0.045 ± 0.007^#★	0.023 ± 0.001^#★	0.030 ± 0.002^#★	0.067 ± 0.005^∗##	0.042 ± 0.005	0.009 ± 0.001^##★★
LHF-H	0.022 ± 0.001	0.014 ± 0.001	0.044 ± 0.003^##	0.037 ± 0.005	0.031 ± 0.006	0.006 ± 0.000
F	51.979	191.059	83.422	56.008	34.994	81.270
	<0.01	<0.01	<0.01	<0.01	<0.01	<0.01

Notes: sham: control group; model: model group; perindopril: perindopril group; LHF-L: low-dose LHF group; LHF-M: medium-dose LHF group; LHF-H: high-dose LHF group. Data are expressed as mean ± standard deviation (SD). , compared with Sham; , compared with model; , compared with perindopril; , compared with LHF-H; , compared with LHF-M.