Evidence-Based Complementary and Alternative Medicine / 2020 / Article / Tab 6

Research Article

Luhong Formula Has a Cardioprotective Effect on Left Ventricular Remodeling in Pressure-Overloaded Rats

Table 6

Col1a1, Col3a1, eNOS, TGF-β1, VEGF, and VEGFR2 relative expression in myocardial tissue of experimental different groups.

GroupCol1a1Col3a1eNOSTGF-β1VEGFVEGFR2

Sham0.015 ± 0.0020.010 ± 0.0010.055 ± 0.0030.020 ± 0.0020.014 ± 0.0010.004 ± 0.000
Model0.080 ± 0.011Δ0.037 ± 0.002Δ0.019 ± 0.001Δ0.124 ± 0.017Δ0.063 ± 0.008Δ0.015 ± 0.001Δ
Perindopril0.029 ± 0.0030.016 ± 0.0010.039 ± 0.0030.047 ± 0.0090.040 ± 0.0040.007 ± 0.001
LHF-L0.063 ± 0.006#★▲0.031 ± 0.001#★▲0.026 ± 0.002#★▲▲0.092 ± 0.007#★▲0.051 ± 0.003##★▲▲0.012 ± 0.001#★▲
LHF-M0.045 ± 0.007#★0.023 ± 0.001#★0.030 ± 0.002#★0.067 ± 0.005∗##0.042 ± 0.0050.009 ± 0.001##★★
LHF-H0.022 ± 0.0010.014 ± 0.0010.044 ± 0.003##0.037 ± 0.0050.031 ± 0.0060.006 ± 0.000
F51.979191.05983.42256.00834.99481.270
<0.01<0.01<0.01<0.01<0.01<0.01

Notes: sham: control group; model: model group; perindopril: perindopril group; LHF-L: low-dose LHF group; LHF-M: medium-dose LHF group; LHF-H: high-dose LHF group. Data are expressed as mean ± standard deviation (SD). , compared with Sham; , compared with model; , compared with perindopril; , compared with LHF-H; , compared with LHF-M.

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