Research Article
Antinociceptive Effects of Shenling Baizhu through PI3K-Akt-mTOR Signaling Pathway in a Mouse Model of Bone Metastasis with Small-Cell Lung Cancer
Figure 3
TUNEL staining of the marrow of tibia in mice with BMLC. Dapi was used to stain nucleus. TUNEL staining (red) indicates apoptosis. Vehicle: BMLC mice treated with placebo (saline). L-D: BMLC mice treated with 15 g·kg−1·day−1 SLBZ-AP for 2 weeks. M-D: BMLC mice treated with 30 g·kg−1·day−1 SLBZ-AP for 2 weeks. H-D: BMLC mice treated with 60 g·kg−1·day−1 SLBZ-AP for 2 weeks. Rapamycin: BMLC mice treated with 4 mg ·kg−1·day−1 rapamycin for 2 weeks.