Antiarthritic and Antihyperalgesic Properties of Ethanolic Extract from Gomphrena celosioides Mart. (Amaranthaceae) Aerial Parts

Figure 9

Effect of the oral administration of EEGC on increase in paw edema (a), mechanical sensitivity (paw withdrawal threshold) (b), and cold hypersensitivity (c) in persistent inflammation induced by the CFA model. Mice were treated once/day for 21 days with saline (0.9%, p.o., control), EEGC (100 mg/kg, p.o.), and dexamethasone (1 mg/kg, i.p.) after CFA. The points are expressed as the mean ± SEM compared with the control vs. treated group.  < 0.05;  < 0.01 or  < 0.001. One-way analysis of variance followed by the Newman–Keuls test.

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