Dipteran Carboxymethyl Chitosan as an Inexhaustible Derivative with a Potential Antiproliferative Activity in Hepatocellular Carcinoma Cells

Figure 6

CM-Ch treatment did not affect body weight, organ weight, and percentage of organ weight relative to body weight in rats. Animals were treated with a single oral dose of either Ca-CM-Ch (1.5 g/kg), Sa-CM-Ch (1.1 g/kg), sy-CM-Ch (1.1 g/kg), or saline (1 mL/kg) as a control. Body weight, organ weight, and percentage of organ weight relative to body weight were measured after 15 days of treatment. Data were represented as mean ± SEM of five animals. Ca-CM-Ch, Chrysomya albiceps CM-Ch; Sa-CM-Ch, Sarcophaga aegyptiaca CM-Ch; sy-CM-Ch, CM-Ch of commercial chitosan. Body and organ weights and percentage of kidney, liver, and spleen organ weight relative to body weight did not significantly differ between treated groups and controls.

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