|
| Study ID | Experimental group | Control group |
| Sample size | Intervention | Specific case | Sample size | Intervention | Specific case |
|
| Liu [39] | 36 | SP (ZFCT[po, 40 mg, tid]) + CPT | Rash or pruritus: 2; gastrointestinal upset: 3; decreased WBC: 1 | 32 | SSZ | Rash or pruritus: 1; gastrointestinal upset: 3; headache: 1 |
| Liu [40] | 30 | SP (ZFCT[po, 80 mg, tid]) + CPT | 0 | 20 | SSZ | 0 |
| Dong [41] | 45 | SP (ZFCT[po, 40 mg, tid]) + CPT | Gastrointestinal upset: 2; drug allergy (SP): 2 | 34 | SSZ + Meloxicam | Gastrointestinal upset: 2; drug allergy (SSZ): 1 |
| Yang [42] | 38 | SP (ZFSRT[po, 60 mg, bid]) + CPT | Rash or pruritus: 4 | 38 | SSZ | 0 |
| Huang [43] | 13 | SP (ZFSRT[po, 60 mg, bid]) + CPT | Rash or pruritus: 1 | 12 | SSZ | Liver and kidney dysfunction: 2 |
| Yin [44] | 31 | SP (ZFSRT[po, 60 mg, bid]) + CPT | Rash or pruritus: 5; gastrointestinal upset: 3; decreased WBC: 2; liver and kidney dysfunction: 1; RBC urine: 4 | 30 | SSZ | Rash or pruritus: 1; gastrointestinal upset: 2; decreased WBC: 2; liver and kidney dysfunction: 2; RBC urine: 3 |
| Lin [45] | 57 | SP (ZFSRT[po, 120 mg, bid]) + CPT | Rash or pruritus: 5; gastrointestinal upset: 7; elevated transaminase: 5 | 58 | SSZ + NSAIDs + methotrexate | Rash or pruritus: 6; elevated transaminase: 6 |
| Jie [47] | 32 | SP (ZFI[intra-articular injection, 35 ml, once a week]) + CPT | Rash or pruritus: 5; dizziness: 1 | 30 | SSZ/Meloxicam | 0 |
| Liu [49] | 60 | SP (ZFSRT[po, 60 mg, bid]) | Rash or pruritus: 3 | 60 | SSZ | Rash or pruritus: 7; elevated transaminase: 3 |
| Chai [50] | 28 | SP (ZFSRT[po, 120 mg, bid]) | Rash or pruritus: 1; gastrointestinal upset: 3; headache: 1 | 22 | SSZ | Rash or pruritus: 2; gastrointestinal upset: 3; decreased WBC: 1 |
|
