Preferential Activity of Petiveria alliacea Extract on Primary Myeloid Leukemic Blast

Figure 1

Relationship between the response to the ex vivo cytotoxicity test with the post-induction remission. (a) Response to idarubicin in primary cells of newly diagnosed acute myeloid leukemia patients. (b) Response to methotrexate in primary cells of newly diagnosed acute lymphoblastic leukemia patients. Red bars show patients who achieved post-induction remission and blue bars show patients who failed to achieve remission. The dotted line represents 1/5 of the IC₅₀, where this cut-off point allows patients to be classified as good or bad responders. (c) Global survival, Kaplan–Meier survival curve of patients with acute leukemia according to the response observed in the ex vivo cytotoxicity test ().

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