Enriched-Baicalein Attenuates Allergy in Cells and Mice

Figure 2

Effect of baicalein on the serum OVA-specific IgE levels in ovalbumin applied Balb/c. Six-week-old Balb/c males were used and OVA was injected intraperitoneally for 0, 7, 14, 21, and 28 days to Balb/c (n = 5). The baicalein, containing 100 mg of baicalein·kg⁻¹ body weight per day dissolved in 0.4% polyethylene glycol in 0.5% EtOH, was applied topically on a daily basis for four weeks. OVA-specific IgE cytokine levels of the serum in mice were determined. OVA-specific IgE antibody was measured using the Mouse OVA-IgE ELISA kit. The absorption of 450 nm (subwavelength, 620 nm) for OVA-specific IgE was measured by a microplate reader. All measurements were made in triplicate and all values are represented as mean ± SD. Nr, normal; OVA-CT, control treated with only ovalbumin; Dexa., dexamethasone. SB, Scutellaria baicalensis Georgi extract. , , and showed a significant difference from OVA-CT.