Study on Intervention Mechanism of Yiqi Huayu Jiedu Decoction on ARDS Based on Network Pharmacology

Figure 3

Construction of YQHYJD-ARDS PPI network. (a) Interactive PPI network of YQHYJD and ARDS with 497 nodes and 3969 edges. (b) First central network evaluation with a core subset of 149 nodes and 2950 edges based on the median degree of 12. (c) Second central network evaluation with a core subset of 61 nodes and 1100 edges based on ““Degree” > 35, “betweenness centrality” >0.002, “closeness centrality” >0.56”. (d) Network diagram of 61 core targets. White nodes, green nodes, and gray nodes stand for common targets, known disease targets, and putative drug targets, respectively.