Pharmacokinetic Herb-Drug Interaction between Hibiscus sabdariffa Calyces Aqueous Extract and Captopril in Rats

Table 1

Gradient profile of the mobile phase used to analyze plasma captopril.

Time (min)	Flow rate (mL/minutes)	0.1% Formic acid in aquadest (%)	Acetonitrile (%)
0	0.2	60	40
1	0.2	10	90
2	0.2	10	90
2.5	0.2	60	40
5	0.2	60	40