Xuan Bi Tong Yu Fang Promotes Angiogenesis via VEGF-Notch1/Dll4 Pathway in Myocardial Ischemic Rats

Figure 2

Myocardial morphology was observed by HE staining (scale bar = 50 μm). Myocardial cells in the control and sham-operated rats were neatly arranged and uniform, without red ischemic changes. Myocardial cells in the model rats were arranged with ambiguous disorder, accompanied by inflammatory cell infiltration, large fiber deposition area, and vascular fibrocyte proliferation. With the increase of XBTYF concentration, inflammatory cell infiltration and vascular proliferation gradually decreased, and the morphology of myocardial cells in high-dose group was similar to that in the control group. (a) Control. (b) Sham-operated. (c) Model rats. (d) XBTYF 3.2 g/kg. (e) XBTYF 1.6 g/kg. (f) XBTYF 0.8 g/kg.

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