Research Article
Xuan Bi Tong Yu Fang Promotes Angiogenesis via VEGF-Notch1/Dll4 Pathway in Myocardial Ischemic Rats
Figure 4
Evaluation of cardiomyocyte apoptosis after XBTYF treatment. (a) Cardiomyocyte apoptosis was detected by TUNEL assay (scale bar = 50 μm). Compared with the model group, cell apoptotic rate decreased gradually with the increase of XBTYF concentration. Values represent the average of three replicates, vs. model. (b) Expression of apoptosis-related proteins Bax, Bcl2, caspase 3, and caspase 9 was assessed by western blot, and the expression of Bax, caspase 3, and caspase 9 was significantly decreased, while Bcl2 expression was increased compared to the model. Values represent the average of three replicates, vs. model.
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