Research Article

Anti-inflammatory Mechanism of Ruzu Bitters on Diet-Induced Nonalcoholic Fatty Liver Disease in Male Wistar Rats

Table 4

Effects of pioglitazone, RUZU, and fenofibrate on the liver index in the experimental groups.

GroupsNormalPIORUZUNAFLDFENO

Liver index (%)3.07 ± 0.03b4.58 ± 0.05ab3.93 ± 0.04ab6.55 ± 0.30a4.94 ± 0.06ab

Values are presented as mean ± SEM (n = 5)., a significant difference compared to normal control. , a significant difference compared to the NAFLD group. NAFLD: nonalcoholic fatty liver disease, PIO: pioglitazone (4 mg/kg body weight), RUZU: Ruzu herbal bitters (0.6 mg/kg body weight), and FENO: fenofibrate (10 mg/kg body weight).