Immunomodulatory Activity of Momordica charantia L. (Cucurbitaceae) Leaf Diethyl Ether and Methanol Extracts on Salmonella typhi-Infected Mice and LPS-Induced Phagocytic Activities of Macrophages and Neutrophils
Table 2
Effect of M. charantia leaf methanol extract on total and differential leucocytes mobilization (cells/ml) in mice.
Extract
Levamisole
Control
250 mg/kg
500 mg/kg
1000 mg/kg
7.5 mg/kg
—
TLC
1416.6 ± 166.55a
1675.6 ± 144.60
1981 ± 461.18
1184.4 ± 149.24
962.28 ± 144.41
NEUT
318.35 ± 147.30
391.04 ± 167.52
462.40 ± 132.83
283,69 ± 75.77
445.53 ± 197.16
(22.09)
(22.95)
(23.44)
(23.82)
(45.68)
LYMPH
1069.60 ± 146.38
1266.06 ± 111.73
1467.92 ± 364.80
892.12 ± 108.61
477.33 ± 153.21
(75.88)
(75.97)
(73.85)
(75.47)
(50.186)
BASO
4.38 ± 4.51
0.03 ± 0.07
0.00 ± 0.00
0.46 ± 0.60
10.11 ± 6.24
(0.29)
(0.00)
(0.00)
(0.04)
(1.07)
MONO
15.10 ± 5.12a
1.22 ± 1.14
30.95 ± 7.59
1.64 ± 0.94
14.06 ± 7.90
(1.07)
(0.07)
(1.61)
(0.13)
(1.50)
EOSIN
0.03 ± 0.06
4.92 ± 2.44
3.93 ± 2.34
5.38 ± 7.09
9.27 ± 6.00
(0.03)
(0.29)
(0.21)
(0.42)
(0.93)
Mean ± SD with different superscript letters is significantly different ().