Research Article

Immunomodulatory Activity of Momordica charantia L. (Cucurbitaceae) Leaf Diethyl Ether and Methanol Extracts on Salmonella typhi-Infected Mice and LPS-Induced Phagocytic Activities of Macrophages and Neutrophils

Table 3

Effect of M. charantia leaf diethyl ether extract on total and differential leucocytes mobilization (cells/ml) in mice.

ExtractLevamisoleControl
250 (mg/kg)500 (mg/kg)1000 (mg/kg)

TLC1356 ± 191.94a1515.8 ± 311.801804.15 ± 322.711151.32 ± 172.10962.28 ± 134.41
Neutrophil311.90 ± 165.23a (22.09)400.09 ± 119.91a (26.37)472.64 ± 116.89a (26.02)303.11 ± 62.80 (26.22)411.43 ± 160.73 (42.92)
Lymphocyte1016.38 ± 95.17 (75.88)1102.57 ± 243.62 (72.78)1289.80 ± 215.62 (71.65)842.42 ± 121.06 (73.28)504.96 ± 170.48 (52.33)
Basophil4.27 ± 4.49 (0.29)0.03 ± 0.07 (0.00)0.00 (0.00)0.45 ± 0.52 (0.04)15.51 ± 4.04 (1.60)
Monocyte16.39 ± 9.32a (1.2)0.63 ± 0.79 (0.04)19.60 ± 3.82a (1.08)1.75 ± 0.48 (0.15)20.23 ± 4.72 (2.10)
Eosinophil0.40 ± 0.91 (0.03)4.81 ± 1.68b (0.32)5.29 ± 0.95b (0.30)0.20 ± 0.46 (0.02)7.05 ± 2.53 (0.71)

Mean ± SD with different superscript letters is significantly different ().