Immunomodulatory Activity of Momordica charantia L. (Cucurbitaceae) Leaf Diethyl Ether and Methanol Extracts on Salmonella typhi-Infected Mice and LPS-Induced Phagocytic Activities of Macrophages and Neutrophils
Table 3
Effect of M. charantia leaf diethyl ether extract on total and differential leucocytes mobilization (cells/ml) in mice.
Extract
Levamisole
Control
250 (mg/kg)
500 (mg/kg)
1000 (mg/kg)
TLC
1356 ± 191.94a
1515.8 ± 311.80
1804.15 ± 322.71
1151.32 ± 172.10
962.28 ± 134.41
Neutrophil
311.90 ± 165.23a (22.09)
400.09 ± 119.91a (26.37)
472.64 ± 116.89a (26.02)
303.11 ± 62.80 (26.22)
411.43 ± 160.73 (42.92)
Lymphocyte
1016.38 ± 95.17 (75.88)
1102.57 ± 243.62 (72.78)
1289.80 ± 215.62 (71.65)
842.42 ± 121.06 (73.28)
504.96 ± 170.48 (52.33)
Basophil
4.27 ± 4.49 (0.29)
0.03 ± 0.07 (0.00)
0.00 (0.00)
0.45 ± 0.52 (0.04)
15.51 ± 4.04 (1.60)
Monocyte
16.39 ± 9.32a (1.2)
0.63 ± 0.79 (0.04)
19.60 ± 3.82a (1.08)
1.75 ± 0.48 (0.15)
20.23 ± 4.72 (2.10)
Eosinophil
0.40 ± 0.91 (0.03)
4.81 ± 1.68b (0.32)
5.29 ± 0.95b (0.30)
0.20 ± 0.46 (0.02)
7.05 ± 2.53 (0.71)
Mean ± SD with different superscript letters is significantly different ().