Evaluation of the Antimalarial Activity of the Hydroalcoholic Extract of Leaf of Leonotis ocymifolia (Burm. f.) Iwarsson (Lamiaceae) against Plasmodium berghei in Mice

Table 3

Antimalarial activity test of the hydroalcoholic extracts of leaf of Leonotis ocymifolia against P. berghei in Rane’s test.

Treatment dose (mg/kg)	Suppression (%)	MSTSEM (days)
CON	—	7.250.46
HA 200 mg/kg	20.57^a3	7.50.92
HA 400 mg/kg	27.75^a3	8.251.39
HA 800 mg/kg	33.44^a3d2	8.630.74^a1
CQ 25 mg/kg	97.10^a3d3e3f3	2800^a3d3e3f3

Data are expressed as mean ± SEM (n = 8); ^acompared to negative control; ^bcompared to CQ 25 mg/kg; ^dcompared to 200 mg/kg; ^ecompared to 400 mg/kg; ^fcompared to 800 mg/kg:  < 0.05,  < 0.01, and  < 0.001; HA, hydroalcoholic; CON, negative control; CQ, chloroquine; MST, mean survival time.