The Antiemetic Effect of Xiao-Ban-Xia-Tang Formula against Cisplatin-Induced Emesis is Mediated through Inhibition of NLRP3 Inflammasome Activation in a Rat Pica Model

<div>Effect of XBXT and ondansetron on histopathological changes in the rat gastric antrum (a) and ileum (b) induced by cisplatin (<i>n</i> = 3). At 72 h after administration of cisplatin or normal saline, the dissected antrum and ileum were fixed with paraformaldehyde (4%) and then embedded in paraffin. Sections were stained with HE. All sections, original magnification ×100. Scale bar = 100 <i>μ</i>m. Nor, normal control group; Cis, cisplatin model group; Ond, ondansetron treatment group; XBXT, XBXT treatment group.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 3: The Antiemetic Effect of Xiao-Ban-Xia-Tang Formula against Cisplatin-Induced Emesis is Mediated through Inhibition of NLRP3 Inflammasome Activation in a Rat Pica Model 

Figure 3 | The Antiemetic Effect of Xiao-Ban-Xia-Tang Formula against Cisplatin-Induced Emesis is Mediated through Inhibition of NLRP3 Inflammasome Activation in a Rat Pica Model 