Evidence-Based Complementary and Alternative Medicine / 2020 / Article / Tab 3 / Research Article
Neuroprotective Effects of D-(-)-Quinic Acid on Aluminum Chloride-Induced Dementia in Rats Table 3 Effect of D-(-)-quinic acid on aluminum chloride-induced dementia in rats as indicated using an actophotometer.
Groups/treatments LA (count/10 min) on 5th day LA (count/10 min) on 16th day LA (count/10 min) on 26th day LA (count/10 min) on 36th day I (control): 0.9% NaCl (5 ml/kg, p.o.) 150.11 ± 1.24 159.34 ± 0.93 155.43 ± 0.91 151.22 ± 1.68 II (inducer): AlCl3 (175 mg/kg, p.o.) 163.47 ± 2.37 89.58 ± 0.63 82.10 ± 1.01 76.82 ± 1.85 III (std.): AlCl3 (175 mg/kg, p.o.)+ rivastigmine (2.5 mg/kg) 145.72 ± 1.03 86.17 ± 0.36 83.09 ± 0.89 143.09 ± 2.46 IV (test A): AlCl3 (175 mg/kg, p.o.) + D-(-)-quinic acid (200 mg/kg, p.o.) 147.29 ± 0.82 84.90 ± 0.45 82.59 ± 0.79 100.49 ± 1.93a b V (test B): AlCl3 (175 mg/kg, p.o.) + D-(-)-quinic acid (400 mg/kg, p.o.) 159.98 ± 1.46 83.75 ± 0.72 83.30 ± 0.67 123.39 ± 2.14a b
Data are presented as mean ± SEM values,
n = 6. Data were analyzed by one-way ANOVA followed by the Tukey–Kramer multiple comparison test
, , , ns when compared with the normal control,
, , , a when compared with the inducer, and
b when compared with the standard.