Study on Anti-Inflammatory Effect and Major Anti-Inflammatory Components of PSORI-CM02 by Zebrafish Model

Figure 3

Regressive effect of inflammation on each experimental group. All zebrafish larvae were incubated in six-well plates, and the capacity of each well was 3 mL. Except for the blank control group, the aqueous solution was given to drugs A, B, and C and indometacin for one hour, respectively. Neutrophils were detected at 2 h after treatment with 10 μM CuSO_4. The positive control was treated with 80 μM indometacin. A: PSORI-CM02 was used at concentrations of 222, 667, and 2000 μg/mL. B: PSORI-CM02 negative drug was used at concentrations 111, 333, and 1000 μg/mL. C: astilbin was used at concentrations 111, 333, and 1000 μg/mL. The number of neutrophils was counted and statistically analyzed. The ratio of inflammatory regression effect was calculated based on the number of neutrophils. N = 10, .