Pentagalloyl Glucose- and Ethyl Gallate-Rich Extract from Maprang Seeds Induce Apoptosis in MCF-7 Breast Cancer Cells through Mitochondria-Mediated Pathway

Table 3

Cytotoxicity of the compounds isolated from maprang seed extracts towards MCF-7, MCF-10A, and MDA-MB-231 cells at 72 h as reflected by IC₅₀ values as determined by MTT assay.

Compounds	MCF-7 IC50 (μg/mL)	MCF-10A IC50 (μg/mL)	MDA-MB-231 IC50 (μg/mL)
MPSE	6.94 ± 1.57	30.08 ± 3.70	18.92 ± 1.20
PGG	>100	>100	26.46 ± 6.53
EG	48.16 ± 0.56	>100	18.04 ± 1.50
GA	26.23 ± 0.24	26.23 ± 0.24	7.39 ± 1.51

Data are represented as IC₅₀ ± SD of three replicates from three independent tests.